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alpha-bromovalerophenone, CAS 49851-31-2, BMF, 2-Bromo-1-Phenyl-Pentan-1-One

alpha-bromovalerophenone CAS 49851-31-2 BMF

2-Bromo-1-Phenyl-Pentan-1-One Introduction:

In the world of organic chemistry, numerous compounds play pivotal roles in various applications. One such compound is 2-Bromo-1-Phenyl-Pentan-1-One, with the chemical formula C11H13BrO. Also known by CAS 49851-31-2, or BMF or alpha-bromovalerophenone, this compound has garnered attention due to its versatile nature and diverse range of applications. In this article, we will explore the synthesis, extraction methods, and notable uses of 2-Bromo-1-Phenyl-Pentan-1-One, shedding light on its significance in both academic research and industrial applications.

alpha-bromovalerophenone, CAS 49851-31-2, BMF, 2-Bromo-1-Phenyl-Pentan-1-One

CAS 49851-31-2 Synthesis and Extraction Methods:

2-Bromo-1-Phenyl-Pentan-1-One can be synthesized using several methods. One common approach is the bromination of 1-phenyl-pentan-1-one using bromine or a brominating agent. The process involves the introduction of a bromine atom into the carbon chain, resulting in the formation of the desired compound. Careful control of reaction conditions, such as temperature and catalysts, is crucial to ensure high yields and selectivity.

Another method of synthesis involves the use of a Grignard reagent, where phenylmagnesium bromide (C6H5MgBr) reacts with 1-bromo-pentan-1-one. This reaction leads to the formation of 2-Bromo-1-Phenyl-Pentan-1-One as the final product.

Extraction methods for obtaining 2-Bromo-1-Phenyl-Pentan-1-One from natural sources are limited since it is predominantly synthesized in laboratories. However, the compound may be extracted from certain plants or organisms that naturally produce it. Further research is needed to explore potential natural sources and extraction techniques.

BMF CAS 49851-31-2 Applications:

Pharmaceutical Industry:

2-Bromo-1-Phenyl-Pentan-1-One finds extensive use in the pharmaceutical industry as a key intermediate in the synthesis of various pharmaceutical compounds. It serves as a valuable building block in the preparation of diverse pharmaceutical agents, including analgesics, sedatives, antihistamines, and anti-inflammatory drugs. The compound’s unique chemical structure allows for modifications that can enhance the biological activity or improve the pharmacokinetic properties of the final pharmaceutical product.

Chemical Research:

Researchers utilize 2-Bromo-1-Phenyl-Pentan-1-One as a precursor in the synthesis of novel compounds for academic research purposes. Its bromine substituent enables the introduction of various functional groups, facilitating the creation of structurally diverse molecules. Moreover, the compound’s reactivity makes it an ideal starting material for the development of new catalysts, ligands, and organic intermediates.

Flavor and Fragrance Industry:

The compound’s aromatic nature lends itself to applications in the flavor and fragrance industry. It serves as a key ingredient in the synthesis of fruity, woody, and floral fragrances due to its pleasant odor profile. Additionally, 2-Bromo-1-Phenyl-Pentan-1-One is often employed as a flavoring agent in the production of food and beverages, contributing to the creation of unique and enjoyable taste experiences.

Organic Synthesis:

Due to its versatile reactivity, 2-Bromo-1-Phenyl-Pentan-1-One is widely used in organic synthesis to introduce the phenyl-pentan-1-one moiety into target molecules. This compound participates in various reactions, such as nucleophilic substitutions, condensations, and cross-couplings, enabling the creation of complex organic structures. Its broad synthetic applications make it a valuable tool for chemists across different industries.

Research on Organometallic Compounds:

2-Bromo-1-Phenyl-Pentan-1-One serves as a precursor in the synthesis of organometallic compounds. These compounds often exhibit unique properties and reactivity, rendering them highly valuable in catalysis and material science. By incorporating 2-Bromo-1-Phenyl-Pentan-1-One into these reactions, researchers can access a wide range of organometallic compounds with tailored structures and functions.


2-Bromo-1-Phenyl-Pentan-1-One, with its distinctive chemical structure and versatile reactivity, has established itself as an invaluable compound in various industries and academic research. Its applications range from pharmaceutical synthesis and chemical research to the flavor and fragrance industry. The compound’s synthetic accessibility and ability to introduce diverse functional groups make it an ideal building block for the creation of novel molecules. Ongoing research and exploration of its properties may uncover further applications, expanding its potential in fields such as material science and catalysis. As scientists delve deeper into the world of organic chemistry, 2-Bromo-1-Phenyl-Pentan-1-One will continue to play a significant role in driving innovation and advancements in diverse scientific fields.

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